反応 #2195506

反応方程式

NaOH

dicyclopentadiene

vinylbenzyl chloride

2,4-dinitrophenol

hydrochloric acid

→

vinylbenzyl ether

収率 95.0%

溶媒

toluene

methyl ethyl ketone

反応条件

後処理

1. 1
   その他equipped with a thermoregulator, stirrer
2. 2
   温度cooling condenser
3. 3
   workup.ADDITIONwas added dropwise at 75° C. to the obtained solution over 20 minutes
4. 4
   その他After the obtained reaction mixture
5. 5
   温度was cooled to room temperature
6. 6
   workup.ADDITIONwas added
7. 7
   洗浄the organic layer was then washed three times with 300 g of distilled water
8. 8
   その他After methyl ethyl ketone was removed under reduced pressure
9. 9
   その他the reaction product was precipitated in 300 ml of methanol
10. 10
    その他to collect solid matter
11. 11
    ろ過through filtration, which
12. 12
    その他was then dried at 50° C. in a vacuum oven

実験手順

45 g (0.25 equivalent) of dicyclopentadiene skeleton phenolic resin, DPP-3H (special phenolic resin manufactured by Nippon Petrochemical Co., Ltd.), 38.1 g of vinylbenzyl chloride CMS-AM (m-/p-isomers: 50/50 wt % mixture) (purity of 91%, 0.25 mol), 2.4 g of tetra-n-butylammonium bromide, 0.038 g of 2,4-dinitrophenol and 200 g of methyl ethyl ketone were charged into a 1-liter four-necked flask equipped with a thermoregulator, stirrer, cooling condenser and dropping funnel and dissolved under agitation, and 40 g of a 50 wt % aqueous solution of NaOH (NaOH purity of 95%, 0.475 mol) was added dropwise at 75° C. to the obtained solution over 20 minutes and further stirred at 75° C. for 4 hours. After the obtained reaction mixture was cooled to room temperature, it was neutralized with 2N hydrochloric acid, 100 g of toluene was added, and the organic layer was then washed three times with 300 g of distilled water. After methyl ethyl ketone was removed under reduced pressure, the reaction product was precipitated in 300 ml of methanol to collect solid matter through filtration, which was then dried at 50° C. in a vacuum oven to obtain a vinylbenzyl ether compound at a yield of 95%. This is designated as compound 3.

出典