反応 #2195488

反応方程式

hydrochloric acid

Triethylamine

sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

dichloromethane

→

trimethylammonium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate

収率 75.0%

溶媒

water

反応条件

後処理

1. 1
   workup.ADDITIONwere added, whereupon the mixture
2. 2
   その他The organic layer was separated
3. 3
   洗浄washed with water
4. 4
   洗浄From the organic layer as washed
5. 5
   workup.DISTILLATIONthe dichloromethane was distilled off in vacuum
6. 6
   workup.ADDITIONDiethyl ether was added to the residue for recrystallization
7. 7
   ろ過The crystals were filtered
8. 8
   その他dried
9. 9
   その他obtaining the target compound in a yield of 75%

実験手順

Triethylamine was dissolved in cold water. To the solution, hydrochloric acid was added, and sodium 1,1,3,3,3-pentafluoro-2-(pivaloyloxy)propanesulfonate prepared in Synthesis Example 27 and dichloromethane were added, whereupon the mixture was stirred. The organic layer was separated and washed with water. From the organic layer as washed, the dichloromethane was distilled off in vacuum. Diethyl ether was added to the residue for recrystallization. The crystals were filtered and dried, obtaining the target compound in a yield of 75%.

出典