反応 #2190777

反応方程式

1-bromo-3,3-dimethylbutane

toluene

triphenyl-phosphine

→

(4-Methyl-pentyl)-triphenyl-phosphonium bromide

反応条件

後処理

1. 1
   温度Cool the reaction mixture down to room temperature
2. 2
   その他isolate the product
3. 3
   その他by crystallization in ether as a white solid (9.8 g)

実験手順

Dissolve 1-bromo-3,3-dimethylbutane(9.6 g, 58.15 mmol) in toluene, add triphenyl-phosphine (13.8 g, 55.2 mmol) and stir at 80° C. for 4 days in a scewcapglass and 3 days in an autoklav at 4 bar and 190° C. Cool the reaction mixture down to room temperature and isolate the product by crystallization in ether as a white solid (9.8 g). MS (m/e): 347 (M+H).

出典