反応 #218402
ord-40171a1ee5944cf5b842d0ec972fa974
反応方程式
2-phenoxymethyl-1-(4-trifluoromethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid
DIC
hexylamine
→
2-Phenoxymethyl-1-(4-trifluoromethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid hexylamide
試薬
なし
溶媒
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1その他The crude material was purified via reversed phase preparative HPLC
実験手順
0.16 mmol of 2-phenoxymethyl-1-(4-trifluoromethoxy-benzyl)-1H-benzoimidazole-5-carboxylic acid were dissolved in 1 ml THF with 1 eq. DIC. After 15 min 1.5 eq of hexylamine were added and the reaction stirred at room temperature for 16 h. The crude material was purified via reversed phase preparative HPLC. MS(ISP): 526.3 (M+H)+.