反応 #2175457

反応方程式

9-formyl-2,7-fluorenedicarboxylic acid dibenzyl ester

hydrogen

hydrogen

→

9-formyl-2,7-fluorenedicarboxylic acid

溶媒

THF

反応条件

後処理

1. 1
   workup.ADDITIONthe Parr bottle was evacuated/filled 3 times on a Parr apparatus
2. 2
   その他the remaining hydrogen was removed at reduced pressure
3. 3
   ろ過The suspension was filtered over a bed of celite
4. 4
   洗浄rinsed with additional THF
5. 5
   その他evaporated

実験手順

In a Parr hydrogenation bottle (Parr Instrument Company, Moline Ill.) was dissolved 9-formyl-2,7-fluorenedicarboxylic acid dibenzyl ester (3.0 g, 0.0061 mol) in THF anh. (350 mL). After careful addition of 20% Pd/C (wet with 50% water) 20% by weight (600 mg), the Parr bottle was evacuated/filled 3 times on a Parr apparatus to ensure hydrogen atmosphere. The suspension was shaken under 20-30 psi hydrogen gas for approximately 60 hours and then the remaining hydrogen was removed at reduced pressure. The suspension was filtered over a bed of celite, rinsed with additional THF and evaporated. 1H-NMR (d6-DMSO): δ (ppm) 9.0 (s, 1H, Ar); 8.5-8.1 (m, 6H, Ar).

出典