反応 #217469
ord-626de5c9f4084cca988b41f92ec68041
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1その他16-Bromohexadecanoic acid was prepared
- 2温度Upon cooling
- 3ろ過It was filtered out
- 4洗浄washed with 3×100 ml of cold water
- 5その他Material was purified by recrystalization from n-hexane
- 6ろ過filtered out
- 7その他dried on high vacuum
実験手順
16-Bromohexadecanoic acid was prepared by refluxing for 48 hrs 5.0 gr (18.35 mmole) of 16-hydroxyhexadecanoic acid in 24 ml of 1:1 v/v mixture of HBr (48% aqueous solution) and glacial acetic acid. Upon cooling, crude product was solidified inside the reaction vessel. It was filtered out and washed with 3×100 ml of cold water. Material was purified by recrystalization from n-hexane, filtered out and dried on high vacuum. 6.1 gr (99% yield) of the desired product were obtained.