反応 #217200

反応方程式

Cn1cnc(C#N)c1

Fc1ccccc1Br

→

Cn1cnc(C#N)c1-c1cccc

収率 2.3%

CC(C)(C)c1ccc(-c2ccc

溶媒

CCCCOC(C)=O

反応条件

後処理

1. 1
   workup.ADDITIONThe plate was removed from the glovebox, opened, and diluted to a 900 uL total volume with N,N-dimethylacetamide. The plate was stirred for 5 min and a 75 uL sample was taken and filtered into an HPLC analysis plate. The filter was rinsed with 400 uL acetonitrile/water (4:1) solution and analyzed by UHPLCMS
2. 2
   workup.STIRRING
3. 3
   workup.ALIQUOT
4. 4
   ろ過

出典