反応 #2171028

反応方程式

1,3-bis-(3,5-dibromo-4-nitropyrazol-1-yl-methyl)benzene

benzylamine

water

→

1,3-bis-(5-benzylamino-3-bromo-4-nitropyrazol-1-yl-methyl)-benzene

溶媒

n-propanol

反応条件

後処理

1. 1
   温度Subsequently the reaction mixture is cooled
2. 2
   ろ過The precipitate is filtered with suction

実験手順

13.9 g of 1,3-bis-(3,5-dibromo-4-nitropyrazol-1-yl-methyl)benzene from step 4.1 are heated together with 6.5 g of benzylamine in 130 ml of n-propanol for 2 hours at 95° C. Subsequently the reaction mixture is cooled and poured into 400 ml water. The precipitate is filtered with suction and recyrstallized from 150 ml of acetonitrile.

出典