反応 #216559

反応方程式

H2O

cyclohexyl bromoacetate

sodium benzenesulfinate dihydrate

→

cyclohexyl benzenesulfonylacetate

収率 76.9%

溶媒

dimethylsulfoxide

反応条件

後処理

1. 1
   その他reacted
2. 2
   温度After cooling
3. 3
   ろ過The precipitate was filtered
4. 4
   洗浄washed with H2O
5. 5
   その他dried

実験手順

To a solution of cyclohexyl bromoacetate (15.6 g, 0.0705 mole) in dimethylsulfoxide (120 ml), sodium benzenesulfinate dihydrate (15 g, 0.075 mole) was added in a small portion at 20°-40° C., and reacted with stirring at 60° C. for 6 hours. After cooling, the reaction mixture was poured into cold H2O (1.5 liter). The precipitate was filtered, washed with H2O and dried to give 15.3 g of cyclohexyl benzenesulfonylacetate as a white crystals having a melting point of 35°-38° C.

出典