反応 #216430

反応方程式

2-aminoethyl thioalaninate dihydrochloride

thre

ammonia

→

2-amino N-(2-mercaptoethyl) propionamide

溶媒

isopropanol

反応条件

後処理

1. 1
   その他The resulting solution is evaporated to dryness under reduced pressure
2. 2
   その他The insoluble ammonium chloride is separated by filtration on fritted glass
3. 3
   その他The filtrate is evaporated to dryness
4. 4
   その他dried under a vacuum at 50° C

実験手順

To a suspension of 22.1 g of the 2-aminoethyl thioalaninate dihydrochloride (0.1 mole), obtained above, in 50 cm3 of isopropanol, thre are slowly added, under an inert atmosphere, 20.4 cm3 (0.15) mole) of a 2.5% aqueous ammonia solution. The resulting solution is evaporated to dryness under reduced pressure. The residue is taken up in 100 cm3 of ethanol. The insoluble ammonium chloride is separated by filtration on fritted glass. The filtrate is evaporated to dryness and dried under a vacuum at 50° C. 17.5 g of 2-amino N-(2-mercaptoethyl) propionamide in the form of a white solid whose melting point is 141° C. are obtained.

出典