反応 #2161254

反応方程式

ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate

→

Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過The reaction solution is then filtered through kieselguhr
2. 2
   濃縮the filtrate is concentrated
3. 3
   その他The residue is dried in vacuo
4. 4
   その他reacted further without further purification

実験手順

0.50 g (2.5 mmol) of ethyl 1-methyl-4-nitro-1H-imidazole-2-carboxylate are dissolved in 7.5 ml of ethanol, 0.13 g (0.13 mmol) of palladium-on-carbon (10%) are added and the mixture is hydrogenated at 3 bar for 12 h. The reaction solution is then filtered through kieselguhr and the filtrate is concentrated. The residue is dried in vacuo and reacted further without further purification.

出典