反応 #2161239

反応方程式

4-tert-butoxyphenyldiphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate

Methanesulfonic acid

→

(4-hydroxyphenyl)diphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate

溶媒

dichloromethane

反応条件

後処理

1. 1
   その他prepared in Synthesis Example 14
2. 2
   温度was heated
3. 3
   洗浄The organic layer was washed with 30 g of water three times
4. 4
   濃縮concentrated
5. 5
   workup.ADDITIONDiethyl ether was added to the
6. 6
   濃縮concentrate for crystallization
7. 7
   ろ過The crystals were filtered
8. 8
   その他dried
9. 9
   その他obtaining the target compound in an amount of 4.9 g

実験手順

In 60 g of dichloromethane was dissolved 6.7 g of 4-tert-butoxyphenyldiphenylsulfonium 1,1,3,3,3-pentafluoro-2-benzoyloxypropane-1-sulfonate (PAG4) prepared in Synthesis Example 14. Methanesulfonic acid, 0.1 g, was added to the solution, which was heated and stirred at 40° C. for 3 hours. The organic layer was washed with 30 g of water three times, and concentrated. Diethyl ether was added to the concentrate for crystallization. The crystals were filtered and dried, obtaining the target compound in an amount of 4.9 g.

出典