反応 #2161223

反応方程式

porphyrin

pyrrole

4-trimethylsilylethynylbenzaldehyde

methanol

→

porphyrin

収率 12.0%

tetrakis(4-trimethylsilylethynylphenyl)porphyrin

収率 12.0%

溶媒

propionic acid

反応条件

後処理

1. 1
   温度The temperature was subsequently increased
2. 2
   温度at reflux for 4 hours
3. 3
   workup.WAITwas then left
4. 4
   その他to crystallize
5. 5
   ろ過The medium was filtered over sintered glass
6. 6
   洗浄the product was rinsed with methanol

実験手順

5.02 g of 4-trimethylsilylethynylbenzaldehyde (25 mmol) were dissolved in 210 ml of propionic acid and then heated to 80° C. 1.72 ml of pyrrole (25 mmol) were subsequently added portionwise over a period of one hour. The temperature was subsequently increased and the mixture was kept at reflux for 4 hours. After a return to ambient temperature, 75 ml of methanol were added to the reaction medium, which was then left to stand for 14 hours in order for the porphyrin to crystallize. The medium was filtered over sintered glass and the product was rinsed with methanol. 2.87 g (3 mmol; yield 12%) of the expected porphyrin (1) were obtained in the form of a purple powder.

出典