反応 #215950

反応方程式

3,4,5,6-tetrahydrophthalic anhydride

diazomethane

methanol

→

title compound

収率 93.0%

Dimethylcyclohex-1-ene-1,2-dicarboxylate

収率 93.0%

溶媒

diethyl ether

反応条件

後処理

1. 1
   温度refluxed for 2 hours
2. 2
   温度The solution was then cooled to ice bath temperature
3. 3
   その他after which time the solvent was removed in vacuo

実験手順

3,4,5,6-tetrahydrophthalic anhydride (3.04 g, 0.02 mol) was disolved in methanol (25 ml) and refluxed for 2 hours. The solution was then cooled to ice bath temperature and a solution of diazomethane in diethyl ether was added dropwise until a yellow colour persisted. The solution was then allowed to stand overnight, after which time the solvent was removed in vacuo to give the title compound In 93% yield. δH (90 MHz, CDCl3) 3.66 (s,6H), 2.20 (s,4H), 1.66 ppm (s,6H)

出典