反応 #215390

反応方程式

product

N,N-di[(2-hydroxy)ethyl]taurine

3,4,5-trimethoxybenzoyl chloride

→

N,N-di-[2-(3,4,5-trimethoxybenzoyloxy)ethyl]taurine

溶媒

ethanol

pyridine

反応条件

後処理

1. 1
   温度It was then cooled to ambient temperature
2. 2
   workup.WAITleft
3. 3
   その他A colourless crystalline compound precipitated which
4. 4
   その他milted at 174°-178° C
5. 5
   その他After recrystallisation from methanol

実験手順

8.5 G of the product obtained in Example 2 (a) was suspended in 25 ml of anhydrous pyridine, and 18.4 g of 3,4,5-trimethoxybenzoyl chloride added slowly under agitation. After being left for one hour at ambient temperature the mixture was heated to 80° C. for a further hour. It was then cooled to ambient temperature, diluted with 50 ml of ethanol and left to stand in a refrigerator. A colourless crystalline compound precipitated which milted at 174°-178° C. After recrystallisation from methanol, the melting point was 180°-183° C. The yield was 11.5 g of pure product.

出典