反応 #215044

反応方程式

mesityl oxide

1,1,3,3-tetramethylbutyl hydroperoxide

→

desired product

2-METHYL-2-(1,1,3,3-TETRAMETHYLBUTYLPEROXY)-4-PENTANONE

反応条件

後処理

1. 1
   workup.ADDITIONwas added slowly
2. 2
   その他The ion-exchange resin was separated by filtration
3. 3
   その他had reacted

実験手順

A mixture of 49 g (0.50 mole) of mesityl oxide and 10 g of Amberlyst 15® sulfonic acid type ion-exchange resin was stirred at 0°-5° C., while 78 g (0.45 mole) of 84% 1,1,3,3-tetramethylbutyl hydroperoxide was added slowly. The reaction mixture was allowed to warm to 25° C. and the stirring continued for 16 hours. The ion-exchange resin was separated by filtration. Iodometric assay showed that substantially all of the hydroperoxide had reacted. The infrared spectrum and G.L.C. showed the presence of the desired product.

出典