反応 #214906

ord-0ca4a9a8b8564ad8b2d091818c6f5ca3

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In a similar operation, 5.0 grams (20 millimoles) of 4-benzhydrylpiperidine in 140 milliliters of dichloromethane was reacted with 2.3 grams (20 millimoles) of diglycolic anhydride in 200 milliliters of dichloromethan to obtain the desired [2-(4-benzhydrylpiperidino)-2-oxoethoxy]acetic acid product as a white solid which after purifying with ethyl acetate-hexane mixture had a m.p. of 139.5°-141° C.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US04256891uspto-grants-1981_03