反応 #214850

反応方程式

1-methylhydantoin

potassium carbonate

2-chloroethyl vinyl ether

dimethylformamide

→

1-Methyl-3-(2-vinyloxyethyl)-hydantoin

溶媒

toluene

反応条件

後処理

1. 1
   その他is reacted for 2 hours and 30 minutes at 130°-138° C.
2. 2
   その他whilst removing
3. 3
   その他the water of reaction
4. 4
   その他are obtained
5. 5
   workup.DISTILLATIONThe crude product is distilled (boiling point 133° C.-134° C./0.2 mm Hg) and 108.5 g (81.8% of theory) of a colourless, viscous distillate
6. 6
   その他are obtained
7. 7
   その他this crystallises

実験手順

A mixture of 82.6 g (0.72 mol) of 1-methylhydantoin, 50.7 g (0.37 mol) of anhydrous potassium carbonate, 89.6 g (0.84 mol) of 2-chloroethyl vinyl ether, 700 ml of dimethylformamide and 100 ml of toluene is reacted for 2 hours and 30 minutes at 130°-138° C., whilst removing the water of reaction. The mixture is then worked up as described in Example 1, and 128.5 g of a clear, reddish brown, viscous crude product (96.9% of theory) are obtained. The crude product is distilled (boiling point 133° C.-134° C./0.2 mm Hg) and 108.5 g (81.8% of theory) of a colourless, viscous distillate are obtained; this crystallises and melts at 54°-56° C.

出典