反応 #214752

反応方程式

N-(3-methyl-2-nitrobenzyl)-L-alanine ethyl ester

hydrogen

→

N-(2-amino-3-methylbenzyl)-L-alanine ethyl ester

溶媒

ethanol

反応条件

後処理

1. 1
   ろ過After completion of the hydrogenation, the catalyst was filtered off
2. 2
   その他the filtrate was evaporated to dryness

実験手順

A solution of 26.6 g of N-(3-methyl-2-nitrobenzyl)-L-alanine ethyl ester in 100 ml of absolute ethanol was hydrogenated in the presence of 2 g of 10% palladium/carbon. 6.7 liters of hydrogen were taken up in 5 hours. After completion of the hydrogenation, the catalyst was filtered off and the filtrate was evaporated to dryness. There was obtained N-(2-amino-3-methylbenzyl)-L-alanine ethyl ester in the form of a yellow oil; [α]D =-52.6° (c=1% in methanol).

出典