反応 #213920

反応方程式

4-dimethoxymethyl-4-trimethylsiloxy-1-octyne

tri-n-butylstannyl hydride

azobisisobutyronitrile

→

title compound

E-1-tri-n-Butylstannyl-4-dimethoxymethyl-4-trimethylsiloxy-1-octene

反応条件

後処理

1. 1
   workup.ADDITIONA mixture of 10.0 g
2. 2
   workup.DISTILLATIONThe excess hydride is distilled off
3. 3
   workup.DISTILLATIONthe residue is purified by molecular distillation (bath temperature=170°-175° C., 0.2mm.)
4. 4
   その他to give 20.5 g

実験手順

A mixture of 10.0 g. (36.7 mmoles) of 4-dimethoxymethyl-4-trimethylsiloxy-1-octyne, 12.82 g. (44 mmoles) of tri-n-butylstannyl hydride 100 mg. of azobisisobutyronitrile is heated to 140° C. under argon for 2 hours. The excess hydride is distilled off and the residue is purified by molecular distillation (bath temperature=170°-175° C., 0.2mm.) to give 20.5 g. of the title compound.

出典