反応 #2133

反応方程式

diethyl [3-(3-methyl-xanthin-1-yl)propyl]phosphonate

chloromethylcyclopropane

→

Diethyl [3-(7-cyclopropylmethyl-3-methylxanthin-1-yl)propyl]phosphonate

反応条件

後処理

1. 1
   その他chromatographed on silica gel (eluent: dichloromethane/methanol 20:1)

実験手順

The title substance was prepared from 0.015 mol of diethyl [3-(3-methyl-xanthin-1-yl)propyl]phosphonate (Example 42), and 0.017 mol of chloromethylcyclopropane analogously to Example 30 and chromatographed on silica gel (eluent: dichloromethane/methanol 20:1).

出典