反応 #2122518

反応方程式

Compound 20

N,N-dihexyl-2-methylbenzo[d]thiazole-6-sulfonamide

p-toluenesulfonic acid methyl ester

hexane

→

Compound 21

収率 78.9%

6-(N,N-dihexylsulfamoyl)-2,3-dimethylbenzo[d]-thiazole-3-ium tosylate

収率 78.9%

溶媒

ethyl acetate

反応条件

後処理

1. 1
   温度to cool to room temperature
2. 2
   その他A sticky dark brown solid separated which
3. 3
   洗浄was washed with hexane
4. 4
   その他dried under vacuum

実験手順

A mixture of Compound 20 (2.0 g, 5.0 mmol) and p-toluenesulfonic acid methyl ester (1.4 g, 7.5 mmol) was heated in a pressure tube at 130° C. for 2 hours. The mixture was allowed to cool to room temperature, and the resulting mass was dissolved in ethyl acetate (4 ml). The combined mixture was then added drop wise to hexane (40 ml). A sticky dark brown solid separated which was washed with hexane and dried under vacuum to yield 2.3 g (78%) of Compound 21 which was used without any further purification. The structure of this compound is given below:

出典