反応 #2082615

反応方程式

H2SO4

Rebaudioside A

KOH

→

rebaudioside C

収率 99.0%

溶媒

methanol

反応条件

後処理

1. 1
   その他to yield a homogeneous solution which
2. 2
   温度was refluxed for 1.5 hours
3. 3
   その他Reaction
4. 4
   温度After cooling to 0°
5. 5
   濃縮The resultant mixture was then concentrated to dryness
6. 6
   その他the residue recrystallized from water

実験手順

Rebaudioside A (0.2 mmol, 183 mg) was transferred to a 15 ml flask. Four ml each of 10% KOH and methanol were added and the resultant mixture heated to yield a homogeneous solution which was refluxed for 1.5 hours. Reaction was then judged complete by TLC analysis. After cooling to 0°; the reaction mixture was acidified to pH 3 with 10% H2SO4. The resultant mixture was then concentrated to dryness and the residue recrystallized from water to give 150 mg (99%) of pure rebaudioside C.

出典