反応 #2075696

反応方程式

4-[4-({2-[(3-{bis[3-(2,2,2-trifluoroacetylamino)propyl]amino}propyl)trifluoro-acetylamino]acetylamino}methyl)-[1,3]dioxolan-2-yloxy]-N,N-ditetradecylbutyramide

sodium hydroxide

→

4-{4-[(2-{3-[bis(3-aminopropyl)-amino]propylamino}acetylamino)methyl]-[1,3]dioxolan-2-yloxy}-N,N-ditetradecylbutyramide

溶媒

tetrahydrofuran

反応条件

実験手順

2.1 g of 4-[4-({2-[(3-{bis[3-(2,2,2-trifluoroacetylamino)propyl]amino}propyl)trifluoro-acetylamino]acetylamino}methyl)-[1,3]dioxolan-2-yloxy]-N,N-ditetradecylbutyramide (1.88 mmol) were dissolved in 30 ml of tetrahydrofuran, and 30 ml of molar sodium hydroxide at 4% were added, with vigorous stirring. The reaction was left overnight at room temperature.

出典