反応 #2069941

反応方程式

Thionyl chloride

4-n-butylbenzyl alcohol

→

title compound

収率 104.9%

1-(Chloromethyl)-4-n-butylbenzene

収率 104.9%

溶媒

ether

反応条件

後処理

1. 1
   その他After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene

実験手順

Thionyl chloride (2.5 ml, 34 mmol) was added to a solution of 4-n-butylbenzyl alcohol (2.0 g, 12 mmol) in ether (25 ml), and this mixture was stirred at room temperature for 3 hours. After concentration of the mixture, excess thionyl chloride was removed by azeotropic distillation with benzene to give the title compound (2.3 g). This compound was used in the following reaction without purification.

出典