反応 #2069924

反応方程式

Acetic anhydride

4-isopropylaniline

→

N-Acetyl-4-isopropylaniline

溶媒

chloroform

反応条件

後処理

1. 1
   温度In the course of this, intense heating of the reaction mixture
2. 2
   workup.ADDITIONOn completion of the dropwise addition
3. 3
   濃縮The reaction mixture is concentrated to dryness
4. 4
   その他the resulting, reddish-white solid is recrystallized from hexane

実験手順

Acetic anhydride (26.0 g, 254 mmol) is slowly added dropwise to a solution of 4-isopropylaniline (17.2 g, 127 mmol) in 80 ml of chloroform. In the course of this, intense heating of the reaction mixture occurs. On completion of the dropwise addition, the mixture is stirred at room temperature for another 2 h. The reaction mixture is concentrated to dryness and the resulting, reddish-white solid is recrystallized from hexane.

出典