反応 #2063054

反応方程式

phthalic anhydride

methylamine

→

N-methylphthalimide

溶媒

water

反応条件

後処理

1. 1
   温度The mixture was heated
2. 2
   温度at reflux for four hours
3. 3
   その他after which approximately 50 ml of the aqueous amine was removed by distillation
4. 4
   温度to cool
5. 5
   ろ過The resultant precipitate was collected by filtration

実験手順

To a suspension of 25.0 g (0.17 mol) of phthalic anhydride in 200 ml of water was added 30 g (0.38 mol) of a 40% aqueous solution of methylamine. The mixture was heated at reflux for four hours, after which approximately 50 ml of the aqueous amine was removed by distillation and the mixture allowed to cool. The resultant precipitate was collected by filtration to yield 10.3 g of N-methylphthalimide (cyclic imide (b)(4)).

出典