反応 #2056

反応方程式

N-methyloctadecylamine

ethylene oxide

→

N-(2-hydroxyethyl)-N-methyloctadecylamine

収率 86.6%

反応条件

後処理

1. 1
   その他An autoclave provided with a stirrer
2. 2
   その他Three hours
3. 3
   workup.ADDITIONthe addition
4. 4
   温度i.e., maintained, at 160° C. for 2 hours
5. 5
   温度cooled
6. 6
   workup.DISTILLATIONdistilled

実験手順

An autoclave provided with a stirrer, a thermometer, a pressure gauge and a pressure dropping funnel was charged with 250 g of N-methyloctadecylamine and heated to 160° C. Then 45 g of ethylene oxide was occasionally added dropwise thereto under a pressure of 0 to 6 kg/cm2G. Three hours were required for completing the addition. Next, the resulting mixture was aged, i.e., maintained, at 160° C. for 2 hours and then cooled. The reaction mixture was taken out and distilled to thereby give 250 g of N-(2-hydroxyethyl)-N-methyloctadecylamine. This product had a boiling point of 185° to 190° C./0.2 mmHg.

出典