反応 #2028931

ord-8b41fe5704804081b2d12efa1f411b07

反応方程式

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
L-Fucose
C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
L-fucose
→
C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO
L-fucitol

反応物

C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
L-Fucose
C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
L-fucose

試薬

[Ni]
Raney-nickel

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

L-Fucose (6-deoxy L-galactose) was reduced [a composition in total of 500 ml containing L-fucose at 1% and 20 ml of the Raney-nickel catalyst] to produce L-fucitol (6-deoxy L-galactitol). FIG. 59(a) shows HPLC analysis results of L-fucose before reduction and FIG. 59(b) shows HPLC analysis results of 6-deoxy D-galactitol after the reduction. The optical rotation of 6-deoxy L-galactitol was −1.7, and FIG. 60 shows 13C NMR spectrum of 6-deoxy D-galactitol.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08389248B2uspto-grants-2013_03