反応 #2028880

反応方程式

3-Methylcatechol

dibromomethane

→

title compound

4-methyl-1,3-benzodioxole

溶媒

H2O

反応条件

後処理

1. 1
   温度the mixture refluxed for an additional 1 hour
2. 2
   workup.DISTILLATIONDistillation of the product from the reaction mixture

実験手順

11.6 g Adogen 464 and 7 mL of dibromomethane were refluxed in 50 mL of H2O for 0.5 hours under argon. 3-Methylcatechol (8.89 g, 71.6 mmol) was added over 2 hours and the mixture refluxed for an additional 1 hour. Distillation of the product from the reaction mixture afforded the title compound as a yellow oil: HRMS m/e 136.0524 (calc'd for C8H8O2, 136.0524).

出典