反応 #2006432

反応方程式

4-nitro-2,2′-bipyridyl-N-oxide

acetyl bromide

→

4-bromo-2,2′-bipyridyl-N-oxide

収率 95.0%

溶媒

acetic acid

反応条件

後処理

1. 1
   温度The yellow mixture was refluxed for 1.5 h
2. 2
   その他The resulting light yellow solid was sufficiently pure enough for the next step without further purification

実験手順

To 4-nitro-2,2′-bipyridyl-N-oxide (Wenkert, D.; Woodward, R. B. J. Org. chem. 48,283 (1983)) (5 g) dissolved in 30 mL acetic acid in a 100 ml round bottom flask was added 16 mL acetyl bromide. The yellow mixture was refluxed for 1.5 h and then rotovaporated to dryness. The resulting light yellow solid was sufficiently pure enough for the next step without further purification. Yield: 95%

出典