反応 #1985944

ord-cf38f96581534566aa8c89c9a242ad2a

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    洗浄the organic layer washed with water, brine
  2. 2
    乾燥dried over magnesium sulfate
  3. 3
    ろ過filtered
  4. 4
    濃縮concentrated in vacuo

実験手順

To a solution of methyl 5-acetoxy-2-formyl-4-methoxyhydrocinnamate (3.31 g) and imidazole (2.42 g) in methylene chloride (25 ml) is added a solution of tert-butylchlorodimethylsilane (2.73 g) in methylene chloride (25 ml). The mixture is stirred at room temperature for about 60 minutes, diluted with ether and water, and the organic layer washed with water, brine, dried over magnesium sulfate, filtered and concentrated in vacuo to give the desired product.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05571506uspto-grants-1996_11