反応 #1985943

反応方程式

methyl 5-acetoxy-2-formyl-4-methoxycinnamate

→

desired product

Methyl 5-Acetoxy-2-formyl-4-methoxyhydrocinnamate

溶媒

ethyl acetate

反応条件

後処理

1. 1
   ろ過filtered
2. 2
   濃縮The filtrate is concentrated in vacuo
3. 3
   その他the residue purified by HPLC
4. 4
   洗浄eluting 50% ethyl acetate in hexanes

実験手順

A mixture of methyl 5-acetoxy-2-formyl-4-methoxycinnamate (10.8 g) and 10% palladium on carbon (3 g) in ethyl acetate (100 ml) is hydrogenated at 45 psi for about 18 hours and filtered. The filtrate is concentrated in vacuo and the residue purified by HPLC, eluting 50% ethyl acetate in hexanes, to give the desired product.

出典