反応 #1981650

ord-e686bfce76a843a28848cd39cd3063b5

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

In a manner analogous to the method described in examples 99, {4-[(4S,5R)-2-(6-tert-butyl-4-ethoxy-pyridin-3-yl)-4,5-bis-(4-chloro-phenyl)-4,5-dimethyl-4,5-dihydro-imidazole-1-carbonyl]-piperazin-1-yl}-acetic acid hydrochloride (example 94) was coupled with 2,6-dimethyl-pyridin-3-ylamine (Alfa) to give the title compound. HR-MS (ES, m/z) calculated for C42H50Cl2N7O3 [(M+H)+] 770.3347, observed 770.3351.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08513239B2uspto-grants-2013_08