反応 #1973965

反応方程式

4-chloro-3-nitroaniline

methanesulfonyl chloride

pyridine

→

title compound

収率 92.2%

N-(4-chloro-3-nitrophenyl)methanesulfonamide

収率 92.2%

溶媒

THF

HCl

反応条件

後処理

1. 1
   ろ過The resulting precipitate was filtered
2. 2
   その他air-dried

実験手順

A mixture of 4-chloro-3-nitroaniline (5.0 g, 29 mmol), methanesulfonyl chloride (2.37 mL, 30.4 mmol) and pyridine (5.9 mL, 72.4 mmol) in THF (100 mL) was stirred for 24 h. Poured in 1M HCl (500 mL). The resulting precipitate was filtered and air-dried to provide the title compound as a solid (6.7 g, 92%).

出典