反応 #1973958

反応方程式

4-bromoaniline

pyridine

(E)-3-methoxyacryloyl chloride

→

title compound

収率 96.0%

(E)-N-(4-bromophenyl)-3-methoxyacrylamide

収率 96.0%

溶媒

CH2Cl2

反応条件

後処理

1. 1
   ろ過The resulting yellow solid was filtered off
2. 2
   洗浄washed with water
3. 3
   その他The solid was dried under vacuum

実験手順

Combined 4-bromoaniline (285 mg, 1.659 mmol), CH2Cl2 (2.0 ml) and pyridine (0.25 ml, 3.09 mmol) and slowly added (E)-3-methoxyacryloyl chloride (200 mg, 1.659 mmol) and stirred at room temperature for 2 h. The resulting yellow solid was filtered off and washed with water. The solid was dried under vacuum to give the title compound (406 mg, 96%).

出典