反応 #1973952

反応方程式

1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-one

1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one

→

(R)-1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-ol

反応条件

後処理

1. 1
   その他The same procedure as in Preparation Example 3
2. 2
   その他prepared in Preparation Example 2

実験手順

The same procedure as in Preparation Example 3 was repeated, with the exception that 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-one, prepared in Preparation Example 2, was used instead of 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one, to afford (R)-1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-ol (hereinafter referred to as “2N alcohol”). The conversion rate and optical purity of the product are given in Table 1, below.

出典