反応 #1973928

ord-2c5e79c602a84d9fa0caec80d5c30337

反応方程式

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid
→
O=C(O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)O
2-(12-phthalimido dodecyl)propane dioic acid
収率 100.0%

反応物

CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
5c
CC(C)(C)OC(=O)C(CCCCCCCCCCCCN1C(=O)c2ccccc2C1=O)C(=O)OC(C)(C)C
2-(12-phthalimido dodecyl)propane dioic acid di-tert-butyl ester
O=C(O)C(F)(F)F
trifluoroacetic acid

試薬

なし

溶媒

ClCCl
dichloromethane

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

Following general procedure D, 16.0 mmol (8.45 g) of 5c and 160 mmol (11.9 mL) of trifluoroacetic acid were reacted in 12 mL of dichloromethane at room temperature and the mixture was processed. Yield 100%.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08501199B2uspto-grants-2013_08