反応 #1951061

反応方程式

Bromotrimethylsilane

cyclopropylmethyl-phosphonic acid diisopropyl ester

→

cyclopropylmethyl-phosphonic acid bis(trimethylsilyl) ester

反応条件

後処理

1. 1
   温度to warm to ambient temperature
2. 2
   workup.STIRRINGstirred for three hours
3. 3
   濃縮concentrated by rotary evaporation

実験手順

Bromotrimethylsilane (43 mL, 0.326 mol) was added dropwise to cyclopropylmethyl-phosphonic acid diisopropyl ester (18.00 g, 81.8 mmol) stirred in a reaction flask chilled to 5° C. The resulting solution was allowed to warm to ambient temperature, stirred for three hours, and then concentrated by rotary evaporation yielding crude cyclopropylmethyl-phosphonic acid bis(trimethylsilyl) ester which was used without further purification.

出典