反応 #1946554

ord-e9c9d541e8334afbbb2a662a6a674734

反応方程式

CCCCCCCCCCCC(=O)N[C@H](C(=O)O)C(C)C
N-lauroylvaline
CC(C)O
isopropanol
O=S(=O)(O)O
sulfuric acid
→
CCCCCCCCCCCC(=O)N[C@H](C(=O)OC(C)C)C(C)C
N-lauroylvaline isopropyl ester

反応物

CCCCCCCCCCCC(=O)N[C@H](C(=O)O)C(C)C
N-lauroylvaline
CC(C)O
isopropanol
O=S(=O)(O)O
sulfuric acid

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    温度The mixture was heated
  2. 2
    温度under reflux for reaction for 6 hours

実験手順

Forty-nine(49) grams of N-lauroylvaline and 197 g of isopropanol were charged into a 500-milliliter flask. Further, 1.61 g of conc. sulfuric acid were added as the catalyst. The mixture was heated under reflux for reaction for 6 hours.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US06528068B1uspto-grants-2003_03