反応 #1929009

反応方程式

indole

sodium bisulfite

→

sodium indole-2-sulfonate

収率 91.0%

溶媒

ethanol

water

反応条件

後処理

1. 1
   ろ過The solid precipitate was filtered
2. 2
   洗浄washed with ether
3. 3
   その他dried

実験手順

A solution of 5 g indole in 10 mL ethanol was added to a solution of 8.8 g sodium bisulfite in 30 mL water. The mixture was stirred at room temperature for 12 hrs. The solid precipitate was filtered, washed with ether, and dried to yield sodium indole-2-sulfonate (7.8 g, 91%) as a white solid. The product was used in the next step without further purification. MP>320° C.; IR (KBr, cm−1) 3470, 3250, 1650, 1600, 1490, 1460, 1210, 1170, 1040, 760, 750.

出典