反応 #1929007

反応方程式

indole

sodium bisulfite

→

sodium indole-2-sulfonate

溶媒

ethanol

water

反応条件

後処理

1. 1
   その他the synthesis of 5,6,7-trichlorogramine
2. 2
   ろ過The solid precipitate is filtered
3. 3
   洗浄washed with ether
4. 4
   その他dried

実験手順

FIG. 1b shows the synthesis of 5,6,7-trichlorogramine. A solution of indole (AA) in ethanol is added to a solution of sodium bisulfite in water. The mixture is stirred at room temperature for 12 hrs. The solid precipitate is filtered, washed with ether, and dried to yield sodium indole-2-sulfonate (BB) as a white solid. The sodium indole-2-sulfonate product (BB) is used in the next step without further purification. MP>320° C.; IR (KBr, cm−1) 3470, 3250, 1650, 1600, 1490, 1460, 1210, 1170, 1040, 760, 750.

出典