反応 #1904063
ord-e9cba8c0497a4a0e94664228affdd173
反応方程式
5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-1H-pyrrole-2-carbonitrile
iodomethane
→
5-(5,5-Dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-1-methyl-1H-pyrrole-2-carbonitrile
反応物
試薬
なし
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
Prepared from 5-(5,5-dimethyl-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-7-yl)-1H-pyrrole-2-carbonitrile and iodomethane generally according to the procedure of example 3. 1H-NMR (DMSO-d6) δ 10.06 (s, 1H), 7.40 (d, J=1.87 Hz, 1H), 7.34 (dd, J=1.87, 8.32 Hz, 1H), 7.20 (d, J=8.38 Hz, 1H), 7.03 (d, J=3.99 Hz, 1H), 6.35 (d, J=4.00, 1H), 4.27 (s, 2H), 3.71 (s, 3H), 1.58 (s, 6H); MS (FI) m/z 294 ([M−H]−, 100%)