反応 #1904029

反応方程式

3-(methoxycarbonylmethylene)glutaric acid dimethylester

water

→

3-(methoxycarbonylmethyl)glutaric acid dimethylester

溶媒

methanol

反応条件

後処理

1. 1
   ろ過The solution was filtered through kieselguhr
2. 2
   濃縮concentrated in vacuo

実験手順

3-(methoxycarbonylmethylene)glutaric acid dimethylester (89 g, 267 mmol) in methanol (200 ml) was shaken with (10% palladium on charcoal: 50% water) (9 g) under an atmosphere of hydrogen gas (3.5 bar) for (30 h). The solution was filtered through kieselguhr and concentrated in vacuo to give 3-(methoxycarbonylmethyl)glutaric acid dimethylester as an oil, yield (84.9 g, 94%).

出典