反応 #1893145

ord-156175bc98354e308783b41eafb72a53

反応方程式

CC/C=C\C/C=C\C/C=C\CCCCCCCC(=O)O
linolenic acid
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
linoleic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
γ-linolenic acid
CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O
stearidonic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他results of the feeding experiments with the yeast cells which

実験手順

FIG. 23 shows the results of the feeding experiments with the yeast cells which comprise plasmid pYES52Dest-MaLPAAT (MaB4_AT). In FIG. 23, A/B, the yeast cultures were fed linoleic acid (18:2 Δ9,12). In comparison with the control culture (FIG. 23, A), the yeast cells with the MaLPAAT showed a markedly higher conversion (increased 4-fold) of 18:2 into γ-linolenic acid (18:3 Δ6,9,12), and a 3.5-fold increase of the fatty acid 20:2 Δ11,14 elongated from 18:2. Analogously, when feeding linolenic acid (18:3 Δ9,12,15), a markedly higher conversion rate to give stearidonic acid (18:4 Δ6,9,12,15) and isoarachidonic acid (20:4 Δ8,11,14,17) was observed in comparison with the controls (FIG. 24).

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08354569B2uspto-grants-2013_01