反応 #1884965

反応方程式

N-tert-butyl-(1-methyl)cyclopropylsulfonamide

benzyl bromide

EtOAc

→

N-tert-Butyl-(1-benzyl)cyclopropyl-sulfonamide

収率 60.0%

溶媒

hexane

反応条件

後処理

1. 1
   その他This compound was obtained in 60% yield

実験手順

This compound was obtained in 60% yield using the procedure described for the synthesis of N-tert-butyl-(1-methyl)cyclopropylsulfonamide except 1.05 equivalents of benzyl bromide were used, followed by trituration with 10% EtOAc in hexane: 1H NMR (CDCl3) δ 0.92 (m, 2H), 1.36 (m, 2H), 1.43 (s, 9H), 3.25 (s, 2H), 4.62 (bs, 1H), 7.29-7.36 (m, 5H).

出典