反応 #1869199

反応方程式

2-amino-3-nitro-phenol

imidazole

chloro-triisopropyl-silane

→

oil

収率 105.4%

2-Nitro-6-triisopropylsilanyloxy-phenylamine

収率 105.4%

溶媒

tetrahydrofuran

反応条件

後処理

1. 1
   ろ過After 18 hours the mixture was filtered
2. 2
   workup.ADDITIONdiluted with ethyl acetate
3. 3
   洗浄washed with water
4. 4
   その他dried
5. 5
   その他evaporated

実験手順

A solution of 2-amino-3-nitro-phenol (42.9 g, 278 mmol) and imidazole (28.4 g, 417 mmol) in tetrahydrofuran (750 ml) was treated with chloro-triisopropyl-silane (62.3 g, 323 mmol). After 18 hours the mixture was filtered, diluted with ethyl acetate, washed with water, dried and evaporated to give an oil (91 g).

出典