反応 #1855339

反応方程式

diallyl L-glutamate p-toluene sulfonate

TsOH

diallyl L-glutamate

triphosgene

trietylamine

→

Diallyl L-glutamyl isocyanate

溶媒

toluene

反応条件

後処理

1. 1
   その他to reach room temperature
2. 2
   その他was used without further purification
3. 3
   その他A typical IR spectrum was obtained v=2253 cm−1 (NCO, v. intense)

実験手順

To diallyl L-glutamate p-toluene sulfonate (the TsOH salt of diallyl L-glutamate) (1.08 g, 2.7 mmol, NovaBiochem) and triphosgene (0.30 g, 1.03 mmol) in 20 mL toluene, stirred at −78° C., trietylamine (0.86 mL, 6.2 mmol) was added. After 30 min, the reaction mixture was allowed to reach room temperature and was used without further purification. A typical IR spectrum was obtained v=2253 cm−1 (NCO, v. intense).

出典