反応 #1811

反応方程式

ammonia

isothiocyanatoacetaldehyde dimethyl acetal

→

title compound

N-(2,2-Dimethoxyethyl)thiourea

溶媒

Methanol

反応条件

後処理

1. 1
   濃縮The mixture was concentrated
2. 2
   その他the residue was chromatographed (silica gel, 5% methanol/dichloromethane)

実験手順

Methanol (200 mL) was saturated with ammonia and stirred with isothiocyanatoacetaldehyde dimethyl acetal (5.0 g) for 2 h. The mixture was concentrated and the residue was chromatographed (silica gel, 5% methanol/dichloromethane) to give the title compound.

出典