反応 #1810803

反応方程式

(4-amino-cyclohexyl)-carbamic acid tert-butyl ester

ethoxycarbonyl-isothiocyanat

→

[trans-4-(3-Ethoxycarbonyl-thioureido)cyclohexyl]carbamic acid tert-butyl ester

反応条件

後処理

1. 1
   その他the mixture obtained
2. 2
   その他The precipitate formed
3. 3
   ろ過is filtered
4. 4
   洗浄washed with diethylether

実験手順

To a solution of 1.10 g of (4-amino-cyclohexyl)-carbamic acid tert-butyl ester in 25 ml of EtAc 0.58 ml of ethoxycarbonyl-isothiocyanat are added and the mixture obtained is stirred at RT. The precipitate formed is filtered and washed with diethylether. [trans-4-(3-Ethoxycarbonyl-thioureido)cyclohexyl]carbamic acid tert-butyl ester is obtained.

出典